Half of your life is determined by genetics, and the other half is shaped by your efforts.
Half of who you become is based on your genes, and the other half is about what you put into it.
こんにちは！
ご質問ありがとうございます。
ご質問について、いくつか言い方が考えられますが、例えば、
Half of your life is determined by genetics, and the other half is shaped by your efforts.
とすると、『人生の半分は遺伝、もう半分は[努力](https://eikaiwa.dmm.com/uknow/questions/63290/)で決まる』となります。少し直訳気味なので、
Half of who you become is based on your genes, and the other half is about what you put into it.
としても良いと思います。
参考になれば幸いです。
Half of your life is really a result of your DNA makeup. The other half of your life is decided by the amount of effort you put into things.
この場合、次のような言い方ができますよ。
ーHalf of your life is really a result of your DNA makeup. The other half of your life is decided by the amount of effort you put into things.
「人生の半分は遺伝、もう半分は努力で決まる」
DNA makeup「DNAの構成」＝「遺伝」
the amount of effort you put into things で「あなたが物事に注ぎ込む努力の量」
ご参考まで！
日本 
カナダ 
